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The Impact of Supplemental MacularCarotenoids in Alzheimer’s Disease:A Randomized Clinical Trial

Nolan JM. Loskutova E. Howard A. Mulcahy R. Stack J. Bolger M. Coen RF. Dennison J. Akuffo KO. Owens N.Power R. Thurnham D. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract. Background: Patients with Alzheimer’s ...

Sustained supplementation and monitored response with differing carotenoidformulations in early age-related macular degeneration

Akuffo BO. Nolan JM. Howard AN. Moran R. Klien R. Klien BE. Meuer SM. Sabour-Pickett S. Thumham DI. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease To compare the impact of sustained supplementation using different macul ...

Prevalence of age-related macular degeneration inthe Republic of Ireland

Akuffo BO. Nolan JM. Stack J. Moran R. Feeney J. Kenny RA. Peto T. Dooley C. Corcoran AM. Cronin H. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease ABSTRACT Background Age-related macular degeneration (AMD) remains the m ...

Cognitive Function and Its Relationshipwith Macular Pigment Optical Densityand Serum Concentrations of its Constituent Carotenoids

Kelly D. Coen RF. Akuffo BO. Beatty S. Dennison J. Moran R. Stack J. Howard AN. Mulcahy R. Nolan JM. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease A bstract. Background: Macular pigment (MP) levels correlate with brain concentra ...

Visual Function and Its Relationship with Severity of Early, and Activity ofNeovascular, Age-Related Macular Degeneration

Loughman J. Sabour-Pickett S. Nolan JM. Klien B. Klien R. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Purpose: To investigate the relationship between visual function and severity of early age-related macular degener ...

Assessment of lutein, zeaxanthin andmeso-zeaxanthin concentrations in dietarysupplements by chiral high-performanceliquid chromatography

Prado-Cabrero A. Beatty S. Stack J. Howard AN. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract We investigated the concordance between actual and declared content of the three macular carot- enoids in commerciall ...

Concordance of Macular Pigment Measurement UsingCustomized Heterochromatic Flicker Photometry and FundusAutofluorescence in Age-Related Macular Degeneration

Prado-Cabrero A. Beatty S. Stack J. Howard AN. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. We compared macular pigment (MP) measurements using customized heterochro- matic flicker photometry (Macular Metrics ...

Lutein, zeaxanthin andmeso-zeaxanthin content of eggs laid by henssupplemented with free and esterified xanthophylls

Nolan JM. Meagher KA. Howard AN. Moran R. Thumham DI. Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract The xanthophyll carotenoids lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ) are found at the macula, the c ...

The Impact of Cataract, and Its Surgical Removal, onMeasures of Macular Pigment Using the HeidelbergSpectralis HRAþOCT MultiColor Device

Akuffo BO. Nolan JM. Stack J. Power R. Kirwan C Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. To investigate the effect of cataract (and cataract surgery) on macular pigment (MP) measurements using the Heidelberg Spect ...

Enrichment of Macular Pigment Enhances ContrastSensitivity in Subjects Free of Retinal Disease: CentralRetinal Enrichment Supplementation Trials – Report 1

Nolan JM. Power R. Stringham J. Dennison J. Stack J. Kelly D. Moran R. Akuffo BO. Corcoran L. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. The high-performance visual function associated with central vision ...

Quantificationofzeaxanthinstereoisomersandluteinintroutfleshusingchiralhigh-performanceliquidchromatography-diodearraydetection

Prado-Cabrero A. Beatty S. Stack J. Howard AN. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease In our previous work we identified the presence of meso-zeaxanthin[(3R,30S)- zeaxanthin] in trout flesh and skin(Nolanetal.,20 ...

The evidence informingthe surgeon’sselectionof intraocular lens onthe basis of lighttransmittance properties

Li X. Kelly D. Nolan JM. Dennison JL. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease In recent years, manufacturers and distributors have promoted commercially available intrao- cular lenses (IOLs) with transmittance pr ...

Serum and macular response to carotenoid-enriched egg supplementationin human subjects: the Egg Xanthophyll Intervention clinical Trial (EXIT)

Kelly D. Nolan JM. Howard AN. Stack J. Akuffo KO. Moran R. Themham DI. Dennison J. Meagher KA. Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract The macular carotenoids lutein (L), zeaxanthin (Z) and meso-zeaxanthi ...

Relationship between macular pigment and visualfunction in subjects with early age-related maculardegeneration

Akuffo BO. Nolan Jm. Peto T. Stack J. Leung I. Corcoran L. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease ABSTRACT Purpose To investigate the relationship between macular pigment (MP) and visual function in subjects wit ...

Stability of Commercially Available MacularCarotenoid Supplements in Oil andPowder Formulations

Phelan D. Prado-Cabrero A. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease A bstract: We previously identified that the concentration of zeaxanthin in some commercially available carotenoid supplements did not agree with ...

NON-DIETARY CORRELATES AND DETERMINANTS OF PLASMA LUTEIN AND ZEAXANTHIN CONCENTRATIONS IN THE IRISH POPULATION

Moran R. Nolan JM. Stack J. O'Halloran AM. Feeney J. Akuffo Ko. Kenny RA. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract: Objective: To investigate non-dietary correlates and determinants of plasma lutein ...

Phospholipid oxidation and carotenoid supplementation in Alzheimer’sdisease patients

ademowo OS. Dias HK. Milic I. Devitt A. Moran R. Mulcahy R. Howard AN. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Alzheimer's disease (AD) is a progressive, neurodegenerative disease, characterised by decline of ...

The Impact of Supplemental Antioxidants on VisualFunction in Nonadvanced Age-Related MacularDegeneration: A Head-to-Head Randomized Clinical Trial

Akuffo KO. Beatty S. Peto T. Stack J. Stringham J. Kelly D. Leung I. Corcoran L. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. The purpose of this study was to evaluate the impact of supplemental macular carot ...

Plasma Lutein and Zeaxanthin Are Associated With Better Cognitive Function Across Multiple Domains in a Large Population-Based Sample of Older Adults: Findings from The Irish Longitudinal Study on Aging

Feeney D. Prado-Cabrero A. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract Background: Low blood serum or plasma concentrations of the xanthophyll carotenoids lutein and zeaxanthin have been implicated in poorer ...

Supplemental Retinal Carotenoids EnhanceMemory in Healthy Individualswith Low Levels of Macular Pigmentin A Randomized, Double-Blind,Placebo-Controlled Clinical Trial

Power R. Coen RF. Beatty S. Mulcahy R. Moran R. Stack J. Howard AN. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease A bstract. Background: There is a biologically plausible rationale whereby the dietary carotenoids lutein ...

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